Songkun Su

time: 2020-09-02   author:   

Curriculum Vitae


Songkun Su, Ph. D., Professor                            

Deputy Dean


College of Animal Sciences (College of Bee Science),

  Fujian Agriculture and Forestry University,

  Fuzhou 350002, China


Voice:0086-591-83739448

Fax: 0086-591-83739448

E-mail:susongkun@fafu.edu.cn


RESEARCHINTERESTS:

   Molecular Biology of Honeybee (Molecular base related to traits)

   Honeybee Breeding (High Royal Jelly Yield and Disease Resistance)

   Behavior of Honeybee (Dance Language, Labor Division)

   Functional Factors in Bee Products (Major royal jelly proteins; Microorganism in the process from pollen to bee bread)


ACADEMIC QUALIFICATIONS:

Ph.D. in Agronomy, Zhejiang University, China.

M.S.in Engineering, Zhejiang University, China.

B.S. in Agronomy, Fujian Agriculture University, China.


RESEARCH EXPERIENCE:

  Our major research fields focus on honeybee genetics and breeding, behavior, molecular biology, functional factors in royal jelly, high and new technology applied in pollen process.

(1) We successfullybred Zhenongda No.1 Italian bee breed with high royal jelly and honey production with our colleagues, and continue to cultivate new honey bee breed with high production, anti-chalkbrood, and anti-virus well.

 (2)A new gene chipAgilentof honeybee covering 11689 genes was designed and prepared, and 369 differentially expressed genes were detected between High Royal Jelly Breed and Low Royal Jelly Breed, and three genes were successfully verified to be the molecular markers related to high royal jelly production trait.

(3)We concentrate at the waggle dance behavior of honey bee and try to discover the molecular base (biogenic amines, microRNA, gene expression profile, proteins) relating to the magic communication style in bee world.

(4)We cloned several major royal jelly protein genes (mrjps) of Apis cerana cerana and expressed them in Bombyx mori larvae and determined the functions of their expression products. We extracted functional components from royal jelly using organic membrane and got a patent for this invention.

(5)Using next-generation sequencing technology, we determined and analyzed the digital gene expression profiles and microRNA in foragers, nurse workers, dancers of Apis mellifera ligustica and foragers of Apis cerana cerana.

(6) We discovered the fermentation mechanism from pollen to bee bread and use the principle to process pollen with lactic acid bacteria into artificial bee bread, which is similar to the process from milk to yoghurt. Pollen could be used by human being instead of milk.


RESEARCH COMMUNICATIONS:

2000.05~2000.08  Tetamantti Apiary of Como, Milano, Italy, Modern Beekeeping Technology. Italy

2005.07~2005.11 Bio-center of Wuerzburg University, Study in Professor Juergen Tautz Group, Molecular and Behavior of Bee. Germany

2006.05~2006.05 Research School of Biology Science, The Australian National University, Study in Professor Shaowu Zhang Group, Cognition and Learning Memory of Honeybee. Australia

2006.12~2007.11  Bio-center of Wuerzburg University, Study in Professor Juergen Tautz Group, Molecular and Behavior of Bee. Germany

2009.09~2009.09  Attend 41th Apimondia in Monpelia, France and Visit Bio-center of Wuerzburg University. France

2010.09~2010.09  Research School of Biology, The Australian National University, Study in Professor Shaowu Zhang Group, Cognition and Learning Memory of Honeybee. Australia

2013.09~2013.10  Attend 43th Apimondia in Kiev, Ukraine and Visit Russian Honeybee Institute, Moscow. Ukraine

2015.09~2015.09  Attend 44th Apimondia in Daejeon, Korea

2016.07~2016.08  Visiting Scholar in Michigan State University, University of Illinois, Arizona State University, USDA-ARS, Bee Research Laboratory, Beltsville, USA

2019.09~2019.09  Attend 46th Apimondia in Montreal, Canada





REPRESENTIVE REFEREED JOURNAL ARTICLES:

[1] Zhiguo Li, Mengshang Hou, Yuanmei Qiu, Bian Zhao, Hongyi Nie, Songkun Su*. Changes in antioxidant enzymes activity and metabolomic profiles in the guts of honey Bee (Apis mellifera) larvae infected with Ascosphaera apis. Insects, 2020, 11(7): E419

[2] Hongyi Nie, Xueyan Wang, Supeng Xu, Yan Gao, Yan Lin, Yanan Zhu, Donglin Yang, Zhiguo Li, Songkun Su*. Changes in the gene expression of chalkbrood resistance in Apis mellifera larvae infected by Ascosphaera apis. Apidologie, 2020, 51(1): 35-47.

[3] Muhammad Rizwan, Pingping Liang, Habib Ali, Zhiguo Li, Hongyi Nie, Hafiz Sohaib Ahmed Saqib, Sajid Fiaz, Muhammad Fahad Raza, Aqai Kalan Hassanyar, Qingsheng Niu, Songkun Su*. Population genomics of honey bees reveals a selection signature indispensable for royal jelly production. Molecular and Cellular Probes, 2020, 52: 101542.

[4] Zhiguo Li, Tiantian Yu, Yanping Chen, Matthew Heerman, Jingfang He, Jingnan Huang, Hongyi Nie, Songkun Su*. Brain transcriptome of honey bees (Apis mellifera) exhibiting impaired olfactory learning induced by a sublethal dose of imidacloprid. Pesticide Biochemistry and Physiology, 2019, 156: 36-43.

[5] Zhiguo Li, Jingfang He, Tiantian Yu, Yanping Chen, Wei-fone Huang, Jingnan Huang, Yazhou Zhao, Hongyi Nie, Songkun Su*. Transcriptional and physiological responses of hypopharyngeal glands in honeybees (Apis mellifera L.) infected by Nosema ceranae. Apidologie, 2019, 50(1): 51-62.

[6] Yan Lin, Qiqi Shao, Meng Zhang, Chenyue Lu, Joy Fleming and Songkun Su*. Royal jelly-derived proteins enhance proliferation and migration of human epidermal keratinocytes in an in vitro scratch wound model. BMC Complementary and Alternative Medicine, 2019, 19: 175.

[7] Aqai Kalan Hassanyar, Shaokang Huang, Zhiguo Li, Muhammad Rizwan, Shahid Mehmood, Muhammad Fahad Raza, Muhammad Qasim, Mubasher Hussain, Songkun Su*. Prevalence of bee viruses in Apis cerana cerana populations from different locations in the Fujian Province of China. MicrobiologyOpen, 2019, 8(9): e830.

[8] Muhammad Fahad Raza, Zhiguo Li, Muhammad Rizwan, Aqai Kalan Hassanyar, Songkun Su*. Comparison of learning and memory of eastern (Apis cerana cerana) and western honey bees (Apis mellifera L.) [J]. Applied Ecology and Environmental Research, 2019, 17(2): 4971-4984.

[9] Hongyi Nie, Shupeng Xu, Cuiqin Xie, Haiyang Geng, Yazhou Zhao, Jianghong Li, Wei-fone Huang, Yan Lin, Zhiguo Li and Songkun Su*. Comparative transcriptome analysis of Apismellifera antennae of workers performing different tasks. Molecular Genetics and Genomics, 2018, 293(1): 237-248.

[10] QingyunDiao, Liangxian Sun, HuajunZheng, ZhijiangZeng, …, Fuliang Hu*, Songkun Su* and Jie Wu*. Genomic and transcriptomicanalysis of the Asian honeybee Apiscerana provides novel insights into honeybee biology. Scientific Reports, 2018, 8:822.

 [11] Li Li, Songkun Su*,Clint Perry, Maurice R. Elphick, Lars Chittka*, Eirik Søvik. Large-scale transcriptome changes in the process of long-term visual memory formation in thebumblebee, Bombusterrestris. Scientific Reports, 2018, 8:534.

[12] Hongyi Nie, Haiyang Geng, Yan Lin, Shupeng Xu, Zhiguo Li, Yazhou Zhao and Songkun Su*. Genome-wide identification and characterization of Fox genes in the honeybee, Apis cerana, and comparative analysis with other bee Fox genes. International Journal of Genomics, 2018, 2018: 5702061.

[13] Yazhou Zhao, Jianmei Zhang, Yanping Chen, Zhiguo Li, Hongyi Nie, Wenjun Peng*, and Songkun Su*. Altered serum metabolite profiling and relevant pathway analysis in rats stimulated by honeybee venom: new insight into allergy to honeybee venom. Journal of Agricultural and Food Chemistry, 2018, 66: 871-880.

[14] Yan Lin, Tianbao Chen, Mei Zhou, Lei Wang, Songkun Su* and Chris Shaw.  Ranatensin-HL: A bombesin-related tridecapeptide from the skin secretion of the broad-folded frog, Hylarana latouchii. Molecules, 2017, 22(7), 1110.

[15] Zhiguo Li, Meng Li, Jingfang He, Xiaomeng Zhao, Veeranan Chaimanee, Wei-fone Huang, Hongyi Nie, Yazhou Zhao and Songkun Su*. Differential physiological effects of neonicotinoid insecticides on honey bees: A comparison between Apismellifera and Apiscerana. Pesticide Biochemistry and Physiology, 2017, 140: 1-8.

[16] Zhiguo Li, Meng Li, Huang J, Changsheng Ma, Linchen Xiao, Qiang Huang, Yazhou Zhao, Hongyi Nie and Songkun Su*. Effects of Sublethal Concentrations of Chlorpyrifos on Olfactory Learning and Memory Performances in Two Bee Species, Apismellifera and Apiscerana. Sociobiology, 2017, 64(2): 174-181.

[17] Shuang Zhang, Hongyi Nie, Qiqi Shao, Aqai Kalan Hassanyar and Songkun Su*. RNA-Seq analysis on effects of royal jelly on tumour growth in 4T1-bearing mice. Journal of Functional Foods, 2017, 36: 459-466.

[18] Shuang Zhang, Qiqi Shao, Haiyang Geng, Songkun Su*. The effect of royal jelly on the growth of breast cancer in mice. Oncology Letters, 2017, 14: 7615-7621.

Shuang Zhang, Qiqi Shao, Zhenhuang Shen and Songkun Su*. Immunomodulatory response of 4T1 murine breast cancer model to camellia royal jelly. Biomedical Research, 2017, 28(3): 1223-1230.

[19] Hongyi Nie, Xiaoyan Liu, Jiao Pan, Weifeng Li, Zhiguo Li, Shaowu Zhang, Shenglu Chen, Xiaoqing Miao, Nenggan Zheng and Songkun Su*. Identification of genes related to high royal jelly production in the honey bee (Apismellifera) using microarray analysis. Genetics and Molecular Biology, 2017, 404):781-789.

[20] Wei-fone Huang, Shahid Mehmood, Shaokang Huang, Yue-Wen Chen, Chong-Yu Ko and Songkun Su*. Phylogenetic analysis and survey of Apiscerana strain of sacbrood virus (AcSBV) in Taiwan suggests a recent introduction. Journal of Invertebrate Pathology,2017, 14636-40.

[21]Yuanzhen Liu, Limin Yan,Zhiguo Li,Wei-fone Huang, ShilaPokhrel, S.,Xiaoyan Liuand Songkun Su*. Larva-mediated chalkbrood resistance associated SNP markers in the honey bee Apis mellifera.Insect Molecular Biology, 2016, 25(3): 239-250.

[22]Zhiguo Li, Shaokang Huang, Weifone Huang, Haiyang Geng, Yazhou Zhao, Meng Li, Yanping Chen, Songkun Su*. A scientific note on detection of honey bee viruses in the darkling beetle, an inhabitant in Apis cerana colonies. Apidologie, 2016,47: 759-761.

 [23] Xiangqian Guo#,Songkun Su#, Skogerbø Geir, Wenfeng Li, Zhiguo Li, Shaowu Zhang, Shenglu Chen, Runsheng Chen. Differential expression of miRNAs related to caste differentiation in the honey bee, Apis mellifera. Apidologie, 2015, 11:1-14.

 [24] Zhiguo Li, Songkun Su, Michele Hamilton, Limin Yan, Yanping Chen. The ability to cause infection in a pathogenic fungus uncovers a new biological feature of honey bee viruses. Journal of Invertebrate Pathology, 2014, 120: 18-22.

 [25] Maria Gabrielade Brito Sanchez, Esther Lorenzo, Songkun Su, Fanglin Liu, Yi Zhan and Martin Giurfa. The tarsal taste of honeybees: behavioral and electrophysiological analyses. Frontiers in Behavioral Neuroscience, 2014, 8: 1-16.

 [26] Zhiguo Li, Yanping Chen, Shaowu Zhang, Shenglu Chen, Wenfeng Li, Limin Yan, Liangen Shi, Lyman Wu, Alex Sohr, Songkun Su*. Viral infection affects sucrose responsiveness and homing ability of forager honey bees, Apis mellifera L. PLoS ONE, 2013, 8(10): e77354.

 [27] Wenfeng Li, Zachary Y., Huang, Fang Liu,ZhiguoLi, LiminYan,Shaowu Zhang, Shenglu Chen,Boxiong Zhong, Songkun Su*. Molecular cloning and characterization of juvenile hormone acid methyltransferase in the honey bee, Apis mellifera and its differential expression during caste differentiation. PLoS ONE, 2013, 8(7): e68544.

 [28] Xiangqian Guo#,Songkun Su#, Geir Skogerboe, Shuanjin Dai, Wenfeng Li, Zhiguo Li, Fang Liu,Ruifeng Ni, Yu Guo, Shenglu Chen, Shaowu Zhang, Runsheng Chen. Recipe for a Busy Bee: MicroRNAs in Honey Bee Caste Determination. PLoS ONE, 2013, 8(12): e81661.

 [29] Fang Liu, Wenjun Peng, Zhiguo Li, Wenfeng Li, Li Li, Jiao Pan, Shaowu Zhang, Yungen Miao, Shenglu Chen,Songkun Su*. Next-generation small RNA sequencing for microRNAs profiling in Apis mellifera: comparison between nurses and foragers. Insect Molecular Biology. 2012,21(3): 297-303.

 [30] Li Li, FangLiu, WenfengLi, ZhiguoLi, JiaoPan, LiminYan, ShaowuZhang, Zachary Y., Huang,Songkun Su*. Differences in microRNAs and their expressions between foraging and dancing honey bees, Apis mellifera L.Journal of Insect Physiology, 2012, 58: 1438-1443.

[31] Zhiguo Li, Fang Liu, Wenfeng Li, Shaowu Zhang, Dong Niu, Haisheng Xu, Qihua Hong, Shenglu Chen, Songkun Su*. Differential transcriptome profiles of heads from foragers: comparison between Apis mellifera ligustica and Apis cerana cerana. Apidologie, 2012, 43: 487-500.

[32] Fang Liu, Wenfeng Li, Zhiguo Li, Shaowu Zhang, Shenglu Chen, Songkun Su*. High-abundance mRNAs in Apis mellifera: Comparison between nurses andforagers. Journal of Insect Physiology, 2011, 57: 274-279.

[33] Fang Liu , Songkun Su*, Yuxing Wang, Songfu Pan, Xiaohua ZhengShuangjin Dai and Shenglu Chen. Advanced mechanization of royal jelly production. Bee World, 88(2): 44-45.

 [34]Songkun Su, Fang Cai, Shaowu Zhang, Aung Si, Jurgen Tautz, Shenglu Chen. East learns from west: Asiatic honeybees can understand dance language of European honeybees. PLoS One, 2008, 3 (6): e2365.

[35]Ting Tao, Song-Kun Su*, Yun-Gen Miao, Wan-Fu Yue, Hong-Hu Du, Sheng-Lu Chen, Fang Liu, and Yi Zhan. Expression of Apalbumin1 of Apis cerana cerana in the Larvae of Silkworm, Bombyx mori. Journal of Agricultural and Food Chemistry, 2008, 56 (20), 9464–9468.

 [36]Songkun Su*, Stefan Albert, Shaowu Zhang, Sven Maier, Shenglu Chen, Honghu Du, Jurgen Tautz. Non-destructive genotyping and genetic variation of fanning in a honeybee colony. Journal of Insect Physiology, 2007, 53: 411-417.

 [37]Songkun Su, Stefan Albert, Shenglu Chen, Boxiong Zhong. Molecular cloning and analysis of four cDNAs from the heads of Apis cerana cerana nurse honeybees coding for major royal jelly proteins. Apidologie, 2005 , 36(3): 389-401.

[38]Viera Albertová, Songkun Su, Axel Brockmann, Jürgen Gadau, and Stefan Albert. Genomic organization of the mrjp3 locus of four honeybee species. Journal of Agricultural and Food Chemistry, 2005, 53(20): 8075-8081.

[39] Shenglu Chen, Songkun Su and Xuezhen Lin. An introduction to high-yielding royal jelly production methods in China. Bee World, 2002, 83(2):69-77


(Note: * Corresponding author)



Contact Information:

 Prof. SongkunSu

College of Animal Sciences (College of Bee Science)

 Fujian Agriculture and Forestry University

15#,RdShangxia Dian, Cangshan District,

 Fuzhou, Fujian, China

Phone: +86-591-83739448

E-mails: susongkun@zju.edu.cn,susongkun@fafu.edu.cn, 365634176@qq.com

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