Professor, Doctoral Supervisor
Educational Background:
Ph.D. 2011-2015
Major in Molecular Genetics and Biochemistry, Department of Plant Pathology &
Microbiology, Texas A&M University, U.S.A.
M.Sc. 2006-2009
Major in Biochemistry and Molecular Biology, Fujian Agriculture and Forestry
University, Fujian, China
B.Sc. 2002-2006
Major in Life Science, Fujian Agriculture and Forestry University, Fujian, China
Study Abroad Experience：
Postdoctoral Scholar 2016-2021
Institute for Integrative Genome Biology, and Department of Botany and Plant Sciences, University of California, Riverside.
Research Focus:
Unlike animals, plant cells are encased within cell walls predominantly composed of carbohydrates. Plant growth is highly dependent on the precise control and regulation of the cell wall, facilitating the coordination of growth and development, as well as the ability to adapt and respond to dynamic environmental conditions. During various stages of growth and development, the physical properties of the cell wall undergo continuous modifications. It is likely that plants utilize sensing and signaling systems to detect alterations in the composition and mechanical properties of the cell wall. These systems possess the capability to interpret and transduce extracellular signals across the cell membrane, subsequently initiating specific functional responses. In our lab, the research focuses on the cell wall signaling, studying several inter-linked areas in cell biology, including auxin signaling, mechanical stress stimulates signaling, and the small GTPase-mediated cytoskeleton network. Through a comprehensive approach that integrates molecular biology and cell biology, our objective is to elucidate the intricate molecular mechanisms underlying cell wall signaling. This entails investigating the receptors and signaling pathways associated with the perception of plant cell walls, along with the interconnected regulatory networks and molecular interactions involved in this process.
Selected Publications:
1) Yu, Y., Tang, W., Lin, W., Li, W, Zhou, X., X, T., Yang, Z., et al., (2023) ABLs and TMKs are co-receptors for extracellular auxin, Cell, https://doi.org/10.1016/ j.cell.2023.10.017 (Co-First)
2) Lin, W., Zhou, X., Tang, W., Takahashi, K., Pan, X., Yang, Z., et al., (2021) TMK based cell surface auxin signaling activates cell wall acidification. Nature. 599, 278–282.
3) Lin, W., Tang, W., Anderson, C., Yang, Z. (2021) Arabidopsis pavement cell morphogenesis requires FERONIA binding to pectin for activation of ROP GTPase signaling. Current Biology. 32, 1-11. (Co-First)
4)Lin, W., Li B, Lu, D., Chen, S., Zhu, N., He, P., Shan, L. (2014) Tyrosine phosphorylation of BAK1/BIK1 mediates Arabidopsis innate immunity. Proc NatlAcad Sci USA.10.1073:1318817111.
5）Lin, W., Lu, D., Gao, X., Jiang, S., Ma, X., Wang, W., Mengiste, T., He, P., Shan, L.(2013) Inverse modulation of plant immune and brassinosteroid signaling pathwaysby the receptor-like cytoplasmic kinase BIK1. Proc Natl Acad Sci USA 110: 12114-12119.
Research Projects:
Grant 1: NSFC (National Natural Science Foundation of Chian )
Molecular mechanism for the activation of cell wall acidification by TMK-based auxin signaling
Grant 2: NSFC for Excellent Young Scientists Fund Program(Overseas): Molecular mechanisms controlling plant growth, development, and environmental adaption
Grant3: Sub-project of the National Key Research and Development Program of China
Email：wwlin@fafu.edu.cn；wwlin@126.com